Techniques of uCT Manipulation to Visualize and Score Vertebrae

Live Poster Session: Zoom Link
Thursday, July 30th 1:15-2:30pm EDT

Sarah Shehreen
Sarah Shehreen

Sarah is a rising senior majoring in Neuroscience and Behavior and minoring in College of East Asian Studies. She spends her spare time cooking, watching cooking videos, or forcing her friends to eat her cooking.

Abstract: Our current method of analyzing vertebrae under the microscope uses calcein and alzarine staining to visualize calcified mass. Despite the success of this method, it has limitations like the scales, which block the view of the vertebrae in older fish. Human vertebrae is commonly visualized through X-ray computed tomography or CAT scans. By using micro CAT (uCT) scans on model vertebrae, we can collect data beyond the constraints of age and the position of the fish under the microscope and gain information such as the 3D view of the skeleton, bone density, and shape of spines and ribs for future projects. We use MeshLab, a free online program, to convert these uCT scans into three different formats: the vertebrae with spines and ribs attached, the vertebrae only, and a colored and labeled vertebrae following the system used in Bird et al. We also created an efficient scoring method that will allow us to directly compare uCT data with microscopy data for future projects. We include pictures of the different formats of uCT scans along with an explanation of the conversion procedure. We also make comparisons in data between the side of the vertebrae scored, when it’s scored, and who scores it to show our method of scoring vertebrae in Meshlab is replicable across  the board.

Techniques-of-uCT-Manipulation-to-Visualize-Vertebrae-Sarah-Shehreen

Live Poster Session: Zoom Link
Thursday, July 30th 1:15-2:30pm EDT

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