Molecular Biology and Biochemistry

Molecular Dynamics Studies of the Ribosome CAR Surface

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Live Poster Session: Zoom LinkThursday, July 30th 1:15-2:30pm EDT Abstract: mRNA codons with the sequence GCN are known to be overrepresented at the beginning of the open reading frame (ORF) of highly expressed yeast genes. This conserved periodicity suggests that these GCN repeats may play a role in regulating protein translation. The structural basis of … Read more

Developing a Structural Model of the Msh2-Msh6-Holliday Junction Interaction

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Live Poster Session: Zoom LinkThursday, July 30th 1:15-2:30pm EDT Abstract: The DNA mismatch repair system (MMR) is a highly conserved system from prokaryotes to eukaryotes that plays a key role in recognizing and repairing post-replicative errors. The eukaryotic Msh2-Msh6 heterodimer is responsible for recognizing and repairing single base pair mismatches and short insertion/deletion loops (IDL). … Read more

Potential Binding Partners for H1 histone in the yeast specie, Saccharomyces cerevisiae

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Live Poster Session: Zoom LinkThursday, July 30th 1:15-2:30pm EDT Abstract: The nucleosome is the basic unit of chromatin which folds to form chromosomes, the final structure in which DNA is packaged in the cell. Nucleosomes consist of DNA wrapped around an octamer of four histone proteins, resulting in a bead on a string type structure. … Read more

Metal Regulatory Transcription Factor 1 (MTF1) Interacts with SWI/SNF Chromatin Remodelers to Promote Myogenesis

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Live Poster Session: Zoom LinkThursday, July 30th 1:15-2:30pm EDT Abstract: Myogenesis is the biological process that leads to the development of skeletal muscle from embryonic stages throughout post-natal growth. Differentiation of myoblasts to skeletal muscle cells is governed by a multitude of myogenic factors and transcriptional regulators. Metal-regulatory transcription factor 1 (MTF1) is a conserved … Read more