Mapping and Visualizing the Free Energy Landscape of p53 using Vectors

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Live Poster Session: Zoom Link
Thursday, July 30th 1:15-2:30pm EDT

Nabeel Kemal
Nabeel Kemal

My name is Nabeel Kemal and I am a rising Sophomore planning to double major in Mathematics and Computer Science. This summer I worked as a member of the Thayer Lab studying the free energy landscape of proteins.

Abstract: Under the notion that molecular motions such as protein folding and conformational substate selection are energetically biased, the free energy landscape becomes an integral informational tool in the design of allosteric effectors to control the biological processes of proteins. In order to capture the free energy landscape, vectors can be utilized using magnitudes and angles taken from the output of simulations using Molecular Dynamics (MD) package AMBER. These vectors then can be overlaid onto the molecule of study to visualize the free energy landscape.

ResearchPosterFinal-Nabeel-Kemal

Live Poster Session: Zoom Link
Thursday, July 30th 1:15-2:30pm EDT

1 thought on “Mapping and Visualizing the Free Energy Landscape of p53 using Vectors”

  1. Terrific work on energy landscape this summer, Nabeel! It has been a pleasure having you on our team, taking on a new direction. It is great to see the culmination of your work on the poster. Reading this over, I am energized and enthusiastic about where this project may go in the fall!

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